ING3 (inhibitor of growth family, member 3)
نویسندگان
چکیده
منابع مشابه
Downregulated inhibitor of growth 3 (ING3) expression during colorectal carcinogenesis
BACKGROUND & OBJECTIVES ING3 (inhibitor of growth protein 3) overexpression decreased S-phase cell population and colony-forming efficiency, and induced apoptosis at a p53-mediated manner. The aim of this study was to investigate the clinicopathological and prognostic significance of ING3 expression in colorectal carcinogenesis and subsequent progression. METHODS ING3 expression was examined ...
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Review on SERPINB3, with data on DNA/RNA, on the protein encoded and where the gene is implicated.
متن کاملDown-regulation of the inhibitor of growth family member 4 (ING4) in different forms of pulmonary fibrosis
BACKGROUND Recent evidence has underscored the role of hypoxia and angiogenesis in the pathogenesis of idiopathic fibrotic lung disease. Inhibitor of growth family member 4 (ING4) has recently attracted much attention as a tumor suppressor gene, due to its ability to inhibit cancer cell proliferation, migration and angiogenesis. The aim of our study was to investigate the role of ING4 in the pa...
متن کاملStructure and expression in breast tumors of human TIMP-3, a new member of the metalloproteinase inhibitor family.
A new member of the metalloproteinase inhibitor family of proteins has been cloned from a complementary DNA library derived from a human breast tumor. The isolated complementary DNA contains an open reading frame 633 base pairs long, encoding a polypeptide of 211 amino acids, which has been called tissue inhibitor of metalloproteinase 3 (TIMP-3). This protein displays low sequence similarity to...
متن کاملING3 promotes prostate cancer growth by activating the androgen receptor
BACKGROUND The androgen receptor (AR) is a major driver of prostate cancer, and increased AR levels and co-activators of the receptor promote the development of prostate cancer. INhibitor of Growth (ING) proteins target lysine acetyltransferase or lysine deacetylase complexes to the histone H3K4Me3 mark of active transcription, to affect chromatin structure and gene expression. ING3 is a stoich...
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ژورنال
عنوان ژورنال: Atlas of Genetics and Cytogenetics in Oncology and Haematology
سال: 2017
ISSN: 1768-3262
DOI: 10.4267/2042/62489